Tell Me All About PrEP

Have you heard about PrEP but still have questions swirling in your mind? If you are simply curious about its benefits, I can tell you PrEP has a lot of them. And if you're already considering taking PrEP yourself to take charge of your sexual health, then you'd better know the risks too. Let's not waste any time - let's talk all things PrEP, the best HIV prevention method.

Tell Me All About PrEP

Did You Know?

  • PrEP Effectiveness: PrEP reduces the risk of getting HIV from sex by about 99% when taken as prescribed.
  • PrEP Uptake in the U.S.: As of 2020, an estimated 25% of the 1.2 million Americans who could benefit from PrEP were prescribed it.
  • Global PrEP Users: By the end of 2021, over 1.6 million people worldwide were reported to be taking PrEP.
  • PrEP Awareness: Surveys indicate that awareness of PrEP in high-risk populations varies widely, with some studies showing awareness rates as high as 90% in some groups.
  • Disparities in PrEP Use: In the U.S., Black/African American and Hispanic/Latino communities are less likely to use PrEP compared to their white counterparts, despite higher HIV incidence rates.

What is PrEP?

PrEP stands for Pre-Exposure Prophylaxis. It's a medicine that people who are at high risk of getting HIV can take to protect themselves. If you accidentally come in contact with HIV, PrEP will stop it from taking hold and making you sick.

PrEP gives you more control over your health and reduces the chances of getting HIV if you're in high-risk situations, like having a partner with HIV or enjoying casual sex with multiple partners.

With that said, even with this super shield, it's always important to use other safety measures like condoms and regular check-ups with healthcare experts. That way, you'll have a strong team protecting you from HIV, and you can live your life to the fullest without fear!

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Who should take PrEP?

In short, PrEP is suitable for anyone who's at a risk of HIV transmission. If you're single and ready to mingle, PrEP can be a great option for you. It's an extra layer of defense when you're out there looking for love. You'll be worry-free when having fun and getting to know new people.

If you're in a committed relationship where one partner has HIV, PrEP can be your trusty sidekick too. It protects the partner who doesn't have HIV, allowing you both to have sex without the fear of transmission.

Did You Know?

  • Insurance Coverage: In the U.S., most private insurance plans cover the cost of PrEP. Medicaid coverage varies by state, but the medication is covered in all Medicaid programs.
  • PrEP Cost: Without insurance, the average retail price of PrEP can exceed $1,600 for a month's supply, though generic versions may cost less.
  • Generic PrEP: The first generic version of Truvada for PrEP was approved by the FDA in 2020, offering a more affordable option.
  • PrEP and Gender: Studies show that PrEP is underutilized by women, accounting for only about 7% of all PrEP users in the U.S.
  • Youth and PrEP: Among adolescents (aged 15-19) at risk for HIV, only a small fraction are taking PrEP, despite its proven effectiveness.

How Does PrEP Work Scientifically?

How Does PrEP Work Scientifically

The ingredients of PrEP are called tenofovir and emtricitabine.

When you take it every day, these ingredients travel through your bloodstream and seek out any sneaky HIV particles that may try to invade.

Once they find the particles, tenofovir and emtricitabine block the enzyme that HIV needs to multiply and spread throughout your body. So they stop HIV from growing.

PrEP works best when you take it every single day. And it's only designed to prevent HIV, not other sexually transmitted infections. So, it's always a good idea to use condoms and vaccinations for additional protection against STIs.

How Long Before It Takes Effect?

Take one pill, once a day, every single day. But PrEP needs a little time to gear up and get ready for action. So wait 7 days after you start taking PrEP before you are fully protected from HIV.

The other way is, if you know in advance when you'll be having sex, you should schedule;

  • Two pills 2-24 hours before sex.
  • One pill 24 hours after the first dose.
  • One pill 48 hours after the first dose (24 hours after the second dose).

Did You Know?

  • Global PrEP Goals: UNAIDS set a target for 3 million people at risk of HIV to be on PrEP by 2020, a goal not yet met by the end of the year.
  • Adherence Challenges: Adherence to daily PrEP is crucial for its effectiveness; however, studies show varying adherence rates, with some populations struggling more than others.
  • Side Effects: Common side effects of PrEP include nausea, headache, and stomach pain, but these usually subside over time.
  • Long-term Use: Research indicates that long-term PrEP use is safe, with minimal impacts on kidney function and bone density when monitored.
  • Reduction in New HIV Infections: Areas with high PrEP uptake have reported reductions in new HIV infections, demonstrating its impact on public health.

What Are the Side Effects of PrEP?

The good news is, not everyone experiences side effects, and if they do occur, they tend to be mild and temporary. Here are some possible side effects of PrEP:

  • Upset Stomach: When starting PrEP, you might experience an upset stomach, feeling a bit queasy, or even having some bathroom trips more often than usual. But the issues usually go away on their own with time.
  • Headache Hiatus: Sometimes, PrEP can bring on mild headaches, like a little pressure in your head.
  • Fatigue: Every now and then, PrEP might make you feel a bit tired.
  • Kidney Function: In rare cases, PrEP can affect your kidneys. That's why it's important to have regular check-ups and blood tests to make sure everything is okay.
  • Bone Density: Some people worry about PrEP impacting their bone strength. Well, the effect is generally quite small, but it's always a good idea to stay on top of things by discussing bone health with your doctor when you have a chance.

Ultimately, the benefits of PrEP in preventing HIV transmission outweigh the side effects, and many people take it without major issues.

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Did You Know?

  • Reduction in New HIV Infections: Areas with high PrEP uptake have reported reductions in new HIV infections, demonstrating its impact on public health.
  • PrEP and STIs: While PrEP does not protect against other sexually transmitted infections (STIs), its use is associated with increased STI testing and detection.
  • PrEP in Low-income Countries: Access to PrEP remains limited in many low-income countries, despite high HIV risk.
  • Global Funding for PrEP: International funding for PrEP is increasing, with great contributions from global health organizations like the Global Fund and PEPFAR.
  • PrEP Education: Efforts to educate healthcare providers and at-risk populations about PrEP are crucial for increasing its uptake.
  • Future of PrEP: New forms of PrEP, such as injectables and implants, are under study and may provide more convenient options for users in the future.

What Do They Say About Their Experiences?

Okay, let's talk about the experiences of gay guys who have taken PrEP and had sex with HIV+ guys. As you may have guessed already, their stories can vary. Here are some things they've shared:

  • Peace of Mind: Many guys feel a sense of relief and peace knowing that PrEP is giving them extra protection against HIV. It allows them to enjoy casual sex with less worry.
  • Improved Confidence: Taking PrEP can boost their confidence because whatever situation they're in, knowing they're lowering their risk of HIV.
  • Open Communication: Some guys have found that PrEP sparks conversations about sexual health with their partners. It's like a key to more open and honest discussions, creating stronger connections.
  • Full Sexual Expression: PrEP can enable them to express their sexuality more freely. They can "go with the flow" during without the fear of HIV standing in the way.

How much does PrEP cost?

How much does PrEP cost

The cost of PrEP can vary depending on your location and healthcare system. Generally, without insurance coverage or assistance programs, the estimated cost of brand-name PrEP can range from around $1,500 to $2,000 per month. But don't worry, most people don't pay this much thanks to insurance coverage or assistance programs.

Some insurance plans may cover PrEP entirely, so you may only need to pay a small portion or nothing at all. It's like having a discount coupon that saves you a bunch of money!

Assistance programs and patient assistance programs (PAPs) are making PrEP more affordable. They help reduce or even eliminate the cost of PrEP for those who are uninsured or having a hard time financially.

Additionally, the availability of generic versions of PrEP has brought down the cost - generic ones work just as well and they're more affordable.

Let's Check Yourself Out - Questions & Advice

1. What factors are most important to you when deciding to start PrEP?

  • (a) Effectiveness in preventing HIV: PrEP is highly effective when taken as prescribed.
  • (b) Cost and insurance coverage: There are various programs to assist with the cost. Investigate these options to ensure PrEP is affordable for you.
  • (c) Ease of obtaining the medication: Access to PrEP is becoming easier, with many clinics and pharmacies offering it.
  • (d) Potential side effects: Most people experience few or mild side effects. 
  • (e) Daily adherence requirements: You really need to be consistent. Consider setting reminders to help with daily intake.
  • (f) Partner's HIV status: Knowing your partner's status helps in assessing your own risk and the need for PrEP.
  • (g) Personal lifestyle and risk factors: Assessing your own risk behaviors and lifestyle choices can help determine if PrEP is a good fit for you.

2. Do you think you might be at risk of HIV exposure due to any of the following?

  • (a) Having a partner who is HIV-positive: PrEP will reduce your risk of contracting HIV from your partner.
  • (b) Multiple sexual partners: PrEP is a must if you have multiple partners.
  • (c) Inconsistent condom use: PrEP works as an additional layer of protection if condom use is inconsistent.
  • (d) Injection drug use: PrEP can help reduce the risk associated with sharing needles.
  • (e) Other: Any activity that increases your exposure to HIV might make you a candidate for PrEP.

3. Do you have access to a healthcare provider who can prescribe PrEP?

  • (a) Yes: Schedule an appointment to discuss whether PrEP is right for you.
  • (b) No: Look for local clinics that offer HIV prevention services.
  • (c) Not sure: Check with your insurance or local health department to find providers who can prescribe PrEP.

4. Are you concerned about the cost of PrEP?

  • (a) Yes: There are insurance plans that can help cover the cost of PrEP.
  • (b) No: If you decide PrEP is right for you, the cost won't be a barrier.
  • (c) Maybe: Investigate the cost and available financial assistance programs.

5. How confident are you in taking a daily medication as prescribed?

  • (a) Very confident: Daily adherence is crucial for PrEP to be effective.
  • (b) Somewhat confident: Consider ways to remind yourself to take your medication daily.
  • (c) Not confident: PrEP requires strict adherence. Other HIV prevention methods might be more suitable.

6. Are you concerned about potential side effects of PrEP?

  • (a) Yes: Most side effects are mild and temporary, but it's important to be informed.
  • (b) No: Stay informed about potential side effects and communicate if any arise.
  • (c) Unsure: Learn about the common side effects to make an informed decision.

7. Are you willing to undergo regular HIV testing while on PrEP?

  • (a) Yes: Regular testing is essential to ensure PrEP is effective and safe.
  • (b) No: Regular testing is a requirement for PrEP. Consider alternative prevention methods.
  • (c) Maybe: Understand the importance of regular testing for PrEP users.

8. How would you describe your current sexual health practices?

  • (a) Consistent condom use: Combining PrEP with consistent condom use provides strong protection.
  • (b) Occasional condom use: Combining occasional condom use with PrEP can improve your protection.
  • (c) No condom use: Consider condoms once in a while.
  • (d) Monogamous relationship: If your partner's HIV status is unknown, PrEP will always be an extra protection.
  • (e) Other: Discuss your practices to tailor an HIV prevention strategy.

9. Are you comfortable discussing PrEP with your sexual partners?

  • (a) Yes: Perfect answer!
  • (b) No: Seek advice on how to approach the conversation.
  • (c) Maybe: Building comfort in discussing PrEP can enhance mutual understanding.

10. Are you aware of other HIV prevention methods besides PrEP?

  • (a) Yes: Combine PrEP with other methods for comprehensive protection.
  • (b) No: Explore other HIV prevention methods like condom use, regular testing, and reducing partners.
  • (c) Somewhat: Expand your knowledge on HIV prevention. Combining methods can offer better protection.

Where Can I Get PrEP? 

  • Healthcare Providers: Your friendly neighborhood healthcare provider, such as a doctor, nurse, or clinic can guide you through the process, assess your eligibility, and prescribe PrEP if it's suitable for you.
  • HIV/STI Clinics: Clinics specializing in HIV or STIs are like specialized PrEP hubs. They give comprehensive PrEP care, including prescribing and monitoring.
  • Community-Based Health Centers: These centers are like warm and welcoming hubs that provide healthcare services to the community. They often offer affordable or sliding-scale options, making PrEP accessible to more people.
  • LGBTQ+ Health Centers: There are health centers run by LGBTQ+ members for LGBTQ+ community. They'll give you advice without any homophobic bias, therefore needless to say, you'll feel you're protected by the safe and inclusive environment.
  • Online: Some online pharmacies allow you to consult with healthcare professionals remotely. They can assess your eligibility, provide prescriptions, and deliver PrEP to your doorstep. 

Getting PrEP is about taking control of your health and well-being. Now you know you can stay proactive, but stay safe!

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About the author 

Ray Flexión

Driven by dreams, grounded by reality, taking revenge on life's challenges. Whatever you say, I stand strong. I'm kind-hearted, though unapologetically true to myself. I stumble but I rise. I am who I am , no excuse.

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  1. Hey, I really appreciate this post. I've had some pretty intense experiences myself with some men for the past few years, so I'm eager to take prep regularly. Can you let me know where I can grab it without speaking to a doctor? Looking forward to reading your blog daily.

    1. Hi Sam, thanks for your comment. Is there any reason that you don’t want to speak to your doctor about it? We’ve seen some fake versions and online scammers selling counterfeit or overcharging, you’d better be careful. We wish you all the best.

  2. My ex was hiV+, as soon as prep came out in. the market he started to have affairs with other guys. For years I took care of it destroyed our relationship because of prep. Just saying.

    1. Sorry to hear that Jonnie, I wouldn’t say because of PrEP, the problem was with him entirely. You know that, don’t you?

      1. if prep hadn't existed things would have been different between us. I still can't help but feel prep played a part in our relationship's demise

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